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In the tirzepatide pivotal trials specifically, hair loss was reported in 4.9-5.3% of treatment groups compared to just 0.9% on placebo, yielding a relative risk of 5.67

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Lastly, even though we provided dietary and exercise counseling to all participants, energy intake and physical activity were not measured, which may be a confounding factor of interindividual variability in weight loss between groups

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However, the timing can significantly influence your subjective experience, particularly regarding side effects like fatigue or indigestion