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J Clin Investig 102:19942001

Pharmacologic measures include NSAIDs, local glucocorticoid injections, and experimental chondroprotective drugs (e.g., chondroitin sulfate and glucosamine)

autoimmune disorders and other inflammatory conditions that increase the demand for B6

Sulfasalazine can inhibit system xc, so the combination of DHODH inhibitors and sulfasalazine may become a new strategy for cancer treatment

The hype around glutathione stems from its wide array of potential health benefits

Digestive disorders including Celiac disease, atrophic gastritis, and shortened small intestines can all increase the risk of vitamin B12 deficiency since nutrients arent as easily absorbed