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Lipolysis via the 3-adrenergic receptor (the assumed mechanism) The most accepted hypothesis is that AOD-9604 indirectly activates 3-adrenergic receptors in adipocytes

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Per FDA guidance, GLP-1-based medications are generally approved for adults with a BMI over 30, or over 27 with a qualifying health condition such as type 2 diabetes, high blood pressure, or high cholesterol

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NICE obesity guidance recommends evidence-based interventions including dietary change, physical activity, and licensed medications such as orlistat or semaglutide