PROLOTHERAPY Derived from the Latin word prolo, meaning to proliferate, regenerate or rebuild, this therapy involves the injection of a mildly irritating substance in to a lesion resulting in localized inflammation with increased blood flow
154 Protein denaturation is a biochemical process that disrupts the hydrogen, hydrophobic, and disulfide bonds, which leads to alteration in the structure of the protein
50.5% of patients achieved 15% or more weight loss
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According to NICE guidance and clinical trials, clinically meaningful weight loss occurs over several months of treatment, with continued weight reduction possible over 1218 months when combined with lifestyle modifications
doi: 10.1074/JBC.M000604200 103 MahutBDelclauxCTillie-LeblondIGossetPDelacourtCZerah-LancnerFet al