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Therefore, the ratio between reduced and oxidized forms of GSH is an important indicator of the redox environment and, at the same time, contributes to the accomplishment of the molecular mechanisms underlying cell proliferation, differentiation or death in the form of apoptosis (Dickinson and Forman, 2002)

PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy

Thus, modulating CD22 activity is proposed as a therapeutic strategy to alleviate SLE-associated symptoms

PubMed PMID: 22074294

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Redox homeostasis in cardiac fibrosis: Focus on metal ion metabolism