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Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

Supplemental BH4 restored the lost dopamine response in the brain.[ref] In severe malaria, BH2 levels are increased and BH4 levels are decreased, indicating increased oxidative stress.[ref] Chronic inflammation can cause depression in some people

Possible side effects include flatulence, skin rashes, or cramps

Sibon D, Coman T, Rossignol J, Lamarque M, Kosmider O, Bayard E, et al