GLP-1 receptor agonists can also be considered, though weight loss targets differ: guidelines recommend a 3% to 5% weight loss for lean patients instead of 10% or more for patients with obesity
Specifically, serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured to evaluate liver function, while blood urea nitrogen (BUN) and creatinine were measured to assess kidney function
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The number of animals listed in Supplementary Table S2 represents the final number at the end of the study
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