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Novel nanomolar potency mitochondrial complex I inhibitor IACS-1131 selectively kills OXPHOS-dependent AML cells

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Accordingly, the benefits may go beyond Hcy lowering and generate positive outcomes also independently of the direct effect on Hcy

Future research should focus on elucidating L-carnitine's molecular mechanisms within the hepatic metabolic network and rigorously assessing its safety and efficacy in well-designed clinical trials

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