This dual mechanism consistently produces greater weight loss than single GLP-1 medications like Ozempic in head-to-head clinical trials
Water retention may stack early on
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KER-065 is a modified Activin RII ligand trap that binds GDF8 and Activin A [5], which can be used as a standalone therapy or in combination with glucagon-like peptide-1 (GLP-1) receptor agonists
For others, Evers said the drugs can be a key stepping stone to get approval for or prepare for bariatric surgery when their initial body mass index (BMI) puts them outside surgical safety parameters
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