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doi: 10.1016/0014-3057(93)90250-J

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doi: 10.1126/sciimmunol.abm5505 214 PandayA.SahooM

[30] [31] A 2016 systematic review compared the efficacy of valproate as an add-on for people with schizophrenia: [32] Other uses [edit] Based upon five case reports, valproic acid may have efficacy in controlling the symptoms of the dopamine dysregulation syndrome that arise from the treatment of Parkinson's disease with levodopa

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Its recommended not to freeze (as mentioned) and also to avoid excessive heat