Moreover, pediatric MASLD is associated with T2DM, cardiovascular metabolism, and renal risk, 157 indicating that GLP-1RA can act as a metabolic modifier, thereby improving prognosis, especially in patients who have difficulty adhering to lifestyle changes
Obesity induces PD-1 on macrophages to suppress anti-tumour immunity
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Some GLP-1 agonists have demonstrated cardiovascular risk reduction in clinical trials
Peer review Peer review information Nature Cancer thanks Andrew Hoy, Michael Pollak, ngela Valverde and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
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