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Clinical Perspective In 15 years of obesity medicine practice, Ive watched hundreds of patients achieve dramatic pharmaceutical weight loss

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Semaglutide (Wegovy and Ozempic) is FDA-approved for weight loss and blood sugar management, respectively, when used in combination with lifestyle changes such as increased physical activity and a balanced diet

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The cardiovascular safety of this dose of semaglutide is currently being evaluated in the SELECT trial, where 17,500 individuals with obesity and established CVD are randomised to semaglutide or placebo for 2.5-5 years

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