The overall cardiometabolic benefit of GLP-1RA rapidly expanded beyond the T2DM population, with the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial describing MACE reduction in the population with overweight and obesity, even in the absence of T2DM [14]
The most common adverse events are nausea and vomiting, both of which are usually transient and of mild severity
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In G6PD deficiency, this could theoretically exacerbate a deficiency of NADPH (promoting hemolysis )
Supports immune system function, collagen production, skin and lip health, and tissue repair