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Skin inflammation in acne occurs when clogged pores trigger an immune response to bacteria, excess oil, or irritation

doi: 10.3389/fpsyt.2019.00025 51 HuangCCWeiIHHuangCLChenKTTsaiMHTsaiPet al

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Furthermore, the release of DAMPs mediated by ferroptosis can affect macrophage polarization, and polarization imbalance can lead to various diseases or inflammatory conditions