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doi: 10.3389/fendo.2025.1645041 22 EldorRAvrahamNRosenbergOShpigelmanMGolan-CohenACukierman-YaffeTet al

The most commonly prescribed medications through such platforms include GLP-1 receptor agonists (such as semaglutide and liraglutide) and orlistat

Fecal excretion of total carnitine was less than 1% of the administered dose.10 After attainment of steady state following 4 days of oral administration of CARNITOR Tablets (1980 mg q12h) or Oral Solution (2000 mg q12h) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12h) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)

Conclusion Hair loss on GLP1 medications is a real concern, but it is almost always temporary telogen effluvium driven by rapid weight loss rather than permanent follicle damage

Novel small molecule inhibitors of nicotinamide N-methyltransferase (NNMT)