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J Immunotherapy

Figure 1 By carefully adjusting factors such as substrate stiffness, topographical cues, and fluid flow patterns, OoC technology enables the incorporation of one or more cell types within a single or interconnected device effectively mimicking various organ functions in a controlled environment ( Therefore, the ability to replicate human physiological complexity more accurately by modulating the 3D microenvironment, and applying various physical stimuli, underscores the significant value of OoC technology across several pivotal areas of research, from pathophysiology studies to personalized therapeutics

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Funding Open access funding provided by North-West University

USP7 regulates HMOX-1 via deubiquitination to suppress ferroptosis and ameliorate spinal cord injury in rats

An iron supplement may be necessary to restore iron to optimal levels (26)