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and 48% at 60 minutes, P = 0.005) (Supplemental Figure 11)

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The two aren't interchangeable, and the expected magnitude of effect isn't comparable - supplements are not positioned by credible sources as equivalent alternatives to prescription GLP-1 medication

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18 Amyloid deposition results in ventricular stiffening and impaired compliance which leads to classic HFpEF symptoms of dyspnea, fatigue, preserved LVEF, and pulmonary hypertension