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This makes sense because growth hormone is naturally released in pulses during deep sleep

Ipamorelin is the ONLY ghrelin mimetic that selectively releases growth hormone without significantly elevating cortisol or prolactin

Osimo EF, Cardinal RN, Jones PB, Khandaker GM

AOD-9604 is a synthetic peptide fragment (amino acids 176-191 of human growth hormone) that stimulates fat breakdown through beta-3 adrenergic receptors in adipose tissue, working peripherally on fat cells rather than centrally on hunger signals