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While early bellwether trials in the GLP-1 MDL may shape outcomes for GI-related claims, this lawsuit remains distinct and may open the door for similar NAION cases in the future

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Ruemmele FM, Beaulieu JF, Dionne S et al (2002) Lipopolysaccharide modulation of normal enterocyte turnover by toll-like receptors is mediated by endogenously produced tumour necrosis factor alpha

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doi: 10.3389/fimmu.2026.1630969 Received 19 May 2025 Revised 07 February 2026 Accepted 09 February 2026 Published 27 February 2026 Volume 17 - 2026 Edited by Pablo Andres Evelson, University of Buenos Aires, Argentina Reviewed by Huanling Lai, Guangzhou National Laboratory, China Neelima Sharma, Birla Institute of Technology and Science, India Updates Copyright 2026 Ni, Chen, Jiang and Huang