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Altern Med Rev 1997;1:155-176 View Full Paper [4] Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C

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Skin inflammation and post-inflammatory hyperpigmentation Overproduction of ROS in melanocytes is also responsible for activation of signaling pathways such as NF-B, MAPK, and JAK/STAT, leading to increased expression of pro-inflammatory cytokines like IL-1, IL-6, and TNF-