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Plasma and RBCs were aliquoted into separate vials and stored at -20C

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For instance, in the subarachnoid hemorrhage model, bromodomain-containing protein 4 (BRD4) was found to bind to H4K8la in astrocytes, and its expression silencing significantly affected the level of this modification, suggesting that BRD4 may serve as a potential reader of H4K8la under this pathological context (Zhang F