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This margin of safety provides reassurance, though caution remains appropriate given the limited formal human studies

Science 314:14611463

Discontinue use if irritation or redness develops

Barrier disruption, in turn, makes bile acids and their harmful metabolites more likely to enter the systemic circulation, thereby activating metabolic and inflammation pathways in the liver and other distal organs, and promoting the progression of NAFLD/non-alcoholic steatohepatitis (NASH) and metabolic diseases, highlighting the impact of bile acids in systemic diseases (Fleishman and Kumar, 2024)

In animal model, the number n = 6 indicated 6 mice in each group

Compound: Bacteriostatic water for research use