The levels of kidney function markers, kidney injury molecules-1 (KIM-1), metallothionein, lipid peroxidation, nitric oxide, tumor necrosis factor-, interleukin-1, and the apoptosis regulators Bax and caspases-3 also increased significantly in the renal tissue of Cd-treated mice, whereas the levels of glutathione, antioxidant enzyme activities, and the apoptosis inhibitor Bcl-2 were significantly reduced in the renal tissue of Cd-treated group
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The noted effectiveness of NaBPC157 in adjuvant arthritis (prophylactic/therapeutic effect, non-established/established adjuvant arthritis) could not be observed with the presently used therapeutic agents
Degeneration in a tendon causes a loss of the normal arrangement of the collagen fibers that join together to form the tendon
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