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Tezspire, the TSLP inhibitor co-commercialised with Amgen for severe uncontrolled asthma, recorded combined worldwide sales of USD 843 million for the nine months to September 2024 growing rapidly as the first biologic targeting TSLP upstream of the inflammatory cascade
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Weight loss tends to become steadier
[7,8] Beyond 6 weeks If a patient has had enough time at an effective dose with tolerable side effects and reasonable adherence, but still shows weak response, it becomes more reasonable to think about genuine low responsiveness, type 2 diabetes-related attenuation of weight-loss effect, or whether another agent may be better