As of April 1, 2026, neither drug is on the shortage list or the 503B bulks list
It is important to note that claims about increased energy expenditure in humans remain insufficiently evidenced at this stage, and the net glycaemic effects reflect observed trial outcomes rather than a straightforward mechanistic reduction in hepatic glucose output the concurrent glucagon receptor agonism may, in fact, influence hepatic glucose production in a complex and not fully characterised manner
Use our GLP-1 (Tirzepatide / Semaglutide) Dose to Units Calculator or the Peptide Calculator above to estimate your dose, syringe units, and mL accurately
Expect retatrutide to list at or slightly above tirzepatide, not below it
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Rotarod Rotarod testing was carried out using the protocol described previously 23