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We previously proposed that autoimmunity contributes to FM based on findings of increased immunoglobulin G binding to satellite glial cells (anti-SGC IgG) in FM subjects compared to healthy controls (HC)
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Additionally, supplementation of L-carnitine enhanced glucose dependent de novo lipogenesis in the absence of ACLY and ACSS2, implicating the carnitine shuttle in transport of acetyl-units out of mitochondria (Figure 6D