Vitamin B2 (Riboflavin) Riboflavin is naturally present in some foods and is an essential component of two major coenzymes that play major roles in energy production, cellular function, metabolism of fats as well as growth and development
That is a meaningful preclinical signal but it is a single research groups model, in one species, without the independent multi-lab replication that would be needed before any human inference
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In: AyersSBaumAMcManusCNewmanSWallstonKWeinmanJWestR, editors
Aging 12 , 1275012770 (2020)
The research indicates upregulation of p53-pS15 and p16 maintains a persistent senescent microenvironment that promotes cell cycle arrest and apoptosis resistance in keloid fibroblasts, perpetuating pathological scar formation