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These agents act through multiple mechanisms, including direct cardioprotection, vasodilation, natriuresis, weight reduction, lipid profile improvement, anti-inflammatory effects, renal protection, reduction in plaque formation, and neurohormonal regulation

Appetite suppression: the first signal Appetite reduction is typically the first noticeable effect

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Newer research indicates they may also be a tool for lowering the risk of heart disease, heart problems, and stroke in patients who are overweight or obese

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