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Potential NAC Side Effects For most people, oral NAC is safe and well-tolerated, meaning its unlikely to cause side effects and is an FDA-approved supplement 42

Arginine increases nitric oxide levels, performs as a vasodilator to improve the availability of oxygen and nutrients to working muscles, reduces the exercise-related accumulation of ammonia

doi: 10.1016/j.ebiom.2020.102913

23 In clinical trials, treatment-discontinuation rates are around 5% to 10%

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