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We employ a pancreatic -cell specific EGFR null mouse (-EGFR fx/fx ) and exogenous exendin-4 treatment to show a role for -cell EGFR in -cell mass, islet size, -cell proliferation, and insulin content

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Cats could soon be offered Ozempic-style weight-loss jabs to help them 'live healthier, longer lives' (stock image) GLP-1 drugs work by mimicking a naturally occurring hormone called glucagon-like-peptide-1, which stimulates insulin production, limits digestion, and creates feelings of fullness

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In this 30-minute EU User Group Meeting talk, they walk through: Why a single tryptic digest leaves complex bispecifics under 75% covered The 9-enzyme combination (3 specific + 6 unspecific) they use to reach 100% Variant Analysis Coverage A side-by-side benchmark of six quantification strategies on a designed 126-variant spike-in dataset The Byologic report-tab setup for weighted quantification across digests and why it lands closest to truth If you're characterising bispecifics, knob-into-hole formats, or any complex multispecific this is the technique pack

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