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Excision also has the advantage over topical treatments of being a one-off treatment that does not rely on patients adhering to a dosing regimen

Phase 2 clinical trial data published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023) demonstrated substantial weight reduction in participants with obesity

produces sustained rather than pulsatile elevation

A: GHK-Cu plasma levels decline ~60% between ages 20-60

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This could be because GLP-1 drugs weaken the brain's link between stimuli and the pleasurable sensations associated with them