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Human genetics of metabolic dysfunction-associated steatotic liver disease: from variants to cause to precision treatment

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Effect of saxagliptin on renal outcomes in the SAVOR-TIMI 53 trial

The most common side effects include nausea, upset stomach, constipation, fatigue, and headaches, which typically resolve with time

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Most participants in trials reached 812 mg weekly, which delivered the strongest results Dosing protocols may be refined in Phase 3 and post-approval, but gradual titration will remain the standard