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Some Another study in healthy adults showed that supplementing with a multivitamin containing high levels of B-complex vitamins for 90 days reduced negative mood symptoms

NK1R antagonists or genetic deletion of NK1R induces anxiolytic and antidepressant-like effects in animal models (Teixeira et al., 1996

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Some people maintain losses for 6+ months with minimal dietary vigilance, while others experience appetite return within 2-3 weeks