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MLCK-mediated intestinal permeability promotes immune activation and visceral hypersensitivity in PI-IBS mice

Consult your healthcare practitioner before use, especially if pregnant, nursing, or taking medications

SUMMARY ANSWER Periconceptional GLP-1 receptor agonist exposure was associated with increased preterm birth risk when used for diabetes treatment (liraglutide aOR 1.70, 95% CI 1.172.48

E., Liew, W

The change from baseline was statistically greater with HS-20094 15 mg compared with semaglutide 1.0 mg (p=0.0024)

For Wegovy (higher-dose semaglutide for weight management), rates were higher, affecting approximately 29.3% of patients across the STEP clinical trials, with most cases occurring during dose escalation phases