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Durnwald, C

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The detrimental effect of oxidative stress is usually accompanied by changes in antioxidant defense mechanisms, with the alterations in antioxidant enzymes expression/activities during MASLD development and progression reported in many clinical and experimental studies

The role for N-acetylcysteine in the management of COPD

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Cytokines such as TNF and IL-6 promote catabolic pathways by activating the ubiquitin-proteasome system while concurrently inhibiting anabolic processes through IGF resistance and irregular mTOR regulation (Kooman et al., 2014