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Without appropriate management, recurrent exposure to stomach acid can damage the lining of the esophagus, leading to complications like esophagitis (inflammation), esophageal stricture (narrowing), or Barretts esophagus, a condition where the tissue lining the esophagus changes and can lead to cancer

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native IGF-1 may allow for more sustained receptor engagement in vitro and in vivo models

The ones cited in every press release announcing this drug as a breakthrough