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Phagocytes recognize and combine with apoptotic cells through phagocytic receptors, that is, Eat me signals are transmitted into phagocytes, which leads to actin polymerization, cytoskeleton rearrangement, and phagocytes extend pseudopodes along the surface of apoptotic cells, which gradually extend to wrap apoptotic cells, and finally fuse to form phagocytes (Zhou and Yu, 2008)

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