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Image processing The detailed image processing statistics are summarized in Supplementary Fig

CNS GIPR KO mice resist development of diet-induced obesity To generate CNS-specific GIPR KO mice, Gipr fl/fl mice 17 were crossed to synapsin-Cre mice (Jackson Laboratories) to obtain Gipr fl/fl control mice and Gipr Syn/ mice (breeding schematic in Fig

Step 5: Label and Refrigerate Standard practice labels the vial with reconstitution date and concentration (40mg/mL) and refrigerates immediately at 36-46F (2-8C)

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This once weekly subcutaneous injection is designed to control brain pressure within hours of administration and dosing lasting a week

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