Using the wrong solvent or contaminated equipment is one of the fastest ways to compromise research materials
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
Poursharifi, P., Madiraju, S
More research is needed to understand the relationship between homocysteine levels, vitamin B12 and cognitive function
Further, we are delaying enforcement (discussed in more detail in section XIX.B.7
Vitamin B12 is an essential nutrient, but injectable treatment still needs to fit the diagnosis, route, and monitoring plan