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Since one of the main concerns about administering pimobendan prior to heart failure always has been that it can cause death, and since death before the usual progression to heart failure always has been considered to be a bad thing and not a desirable one, it would be very curious if death prior to heart failure has been added to the EPIC Trial's objective as a normal, desirable end point

Shetty, A., Hsu, J

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Semaglutide activates GLP-1 receptors, improving glycemic control and promoting modest weight loss