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Isolated cardiomyopathy presenting from 32 weeks in utero to 10 years of age was associated with high mortality in two large Bedouin families with homozygous G555E mutations in the SDHA gene [132]
Early Phase I studies in humans identified 0.025 mg/kg per day (approximately 1.52 mg for an average adult) as an appropriate dose, with measurable tanning observed after just five low doses administered over two weeks [1]
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PMC 1133600
JAMA Internal Medicine, 173 (5), 355-361
Administered by licensed medical professionals: Delivered in a clinical setting by trained staff, ensuring both safety and proper technique
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