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Terms such as antioxidant, epigenetic regulator and neuroprotector describe experimental findings and hypotheses rather than an authorised clinical mechanism

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As there are no definitive markers to determine which patient groups would most benefit from this treatment method, additional research is necessary to clearly define the demographic and clinical factors linked to treatment efficacy (85)

doi: 10.1159/000490384 19 GawakoMBalsamPLodziskiPGrabowskiMKrzowskiBOpolskiGet al

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PRMT5 methylation of H4R3me2s can inhibit gene expression via DNA methylation or histone ubiquitination [68]