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By week six to eight, the majority of users report that digestive symptoms return to baseline or improve significantly

[48] DeFronzo RA

doi: 10.1128/MCB.16.8.4231 185 SiddiqiH

Clinical trials show that GLP1 medications deliver impressive weight loss results for the majority of patients who use them without side effects

However, the efficacy of the thymus diminishes over time, which may lead to tissue damage and diminished immunity

While orthostatic hypotension is not specifically listed in the UK Summary of Product Characteristics (SmPC) for Mounjaro, hypotension and dehydration are recognised as potential adverse reactions, particularly in patients experiencing gastrointestinal side effects