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Any bacterial contamination can lead to enzymatic degradation, effectively destroying the peptide and rendering research results invalid

These observations suggest a significant contribution of CYPOR to NFT-induced Nrf2 activation in the HepG2 model, but also indicate that other cellular flavoprotein reductases are likely to be involved in the formation of the NFT radical anion and its subsequent activation of Nrf2 and synthesis of GCLC and glutathione

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For these truncated proteins we did not observe proteolytic processing suggesting that processing occurs from the N-terminus (Supplementary Fig