Ultimately, regardless of your condition or age, consult your doctor before taking creatine
Pick a rotation pattern and stick with it
'Damage is permanent' Pain in mice triggered the release of adrenaline and cortisol, making their hearts beat faster and blood pressure rise, affecting the nervous system and causing acute stress
Many users report their best results in the first 3 weeks of each cycle precisely because receptor sensitivity is highest at that point
For your next dose, adjust your technique
Puopolo characterized this as evidence that the drugs reach the brain's reward circuitry, with the clearest data so far around alcohol and emerging signals for nicotine, opioids, and compulsive behaviors