The STEP 1 clinical trial, which investigated the efficacy of 2.4 mg semaglutide, included a substudy specifically analyzing body composition via dual-energy X-ray absorptiometry (DEXA) [1]
508,509,510,511 Additionally, GLP-1 mitigates liver inflammation and fibrosis by inhibiting the NF-B pathway, reducing the release of pro-inflammatory cytokines such as TNF- and IL-6, and thus suppressing inflammatory pathways
Taking into account the potential side effects of higher doses
Do not use if you or your family have a history of a type of thyroid cancer called MTC or MEN 2
These formulations are produced by 503A and 503B compounding pharmacies and typically cost a fraction of the brand-name price
Heres how you can obtain a prescription for GLP-1 receptor agonists at our practice: 1