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Brand-name tirzepatide can be very expensive , especially for those without insurance or those whose insurance does not cover the drug

Once reconstituted with bacteriostatic water, ipamorelin must be refrigerated at 28C and used within 28 days to prevent bacterial growth and peptide degradation

While gastrointestinal side effects drove most discontinuations, the requirement for weekly injections contributes to long-term compliance challenges

Salden BN, Monserrat V, Troost FJ, et al

For Canadians looking to address post-weight-loss skin laxity across large body areas like the abdomen, arms, and thighs, injectable GHK-Cu offers a level of systemic reach that topical products simply cannot match

Research is ongoing, but more evidence is needed before regulators consider approval