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27, at UT Southwestern Medical Center

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GLP-1RAs can cross the bloodbrain barrier and activate brain GLP-1 receptors, leading to neuroprotection by improving insulin signaling, reducing tau hyperphosphorylation, and enhancing cognitive function in diabetic and aging models

GLP-1 receptor agonists are a class of medications primarily used to manage type 2 diabetes mellitus and, more recently, obesity

Conclusion In conclusion, CVOTs have played a pivotal role in evaluating the cardiovascular safety and efficacy of GLP-1 receptor agonists in patients with T2D