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The cardiovascular safety data from these trials showed that semaglutide was generally well-tolerated from a cardiac rhythm perspective, with no significant increase in arrhythmias compared to placebo

Both Winterstein, who uses Mounjaro, and Thomas, who uses Ozempic, said that, more so than any physical side effects, the main impact of the medications that they've noticed is the quieting of what they describe as the "food noise" in their heads

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It is currently in phase 3 clinical trials

The superior portals are at or just slightly above the knee cap on either side and are typically injected with the knee held in extension

For a comprehensive overview of GLP-1-class side effects, see our peptide side effects guide