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For example, a 2016 study highlighted how high doses of Vitamin B12, alongside other B vitamins, helped reduce pain and improve nerve conduction in diabetic patients

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These beneficial effects may reflect the known effects of NK1 receptor antagonists on the vomiting center in the brainstem, akin to the action associated with reduced chemotherapy-induced emesis

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On the contrary, remarkably less survived SGNs, more apoptotic SGNs, and the higher expression level of 4-HNE were detected in the peroxynitrite + gpx1 / group compared with the peroxynitrite-only group